King James Version

What Does Mark 16:18 Mean?

Mark 16:18 in the King James Version says “They shall take up serpents; and if they drink any deadly thing, it shall not hurt them; they shall lay hands on the sic... — study this verse from Mark chapter 16 with commentary, cross-references, and original Greek word analysis.

They shall take up serpents; and if they drink any deadly thing, it shall not hurt them; they shall lay hands on the sick, and they shall recover.

Mark 16:18 · KJV


Context

16

He that believeth and is baptized shall be saved; but he that believeth not shall be damned.

17

And these signs shall follow them that believe; In my name shall they cast out devils; they shall speak with new tongues;

18

They shall take up serpents; and if they drink any deadly thing, it shall not hurt them; they shall lay hands on the sick, and they shall recover.

19

So then after the Lord had spoken unto them, he was received up into heaven, and sat on the right hand of God.

20

And they went forth, and preached every where, the Lord working with them, and confirming the word with signs following. Amen.


Commentary

KJV Study Commentary
They shall take up serpents (ὄφεις ἀροῦσιν, opheis arousin)—likely refers to Acts 28:3-5 where Paul survived a viper bite. If they drink any deadly thing, it shall not hurt them (κἂν θανάσιμόν τι πίωσιν οὐ μὴ αὐτοὺς βλάψῃ)—not permission to test God by deliberately handling snakes or drinking poison, but promise of divine protection in unavoidable danger during kingdom mission.

They shall lay hands on the sick, and they shall recover (ἐπὶ ἀρρώστους χεῖρας ἐπιθήσουσιν καὶ καλῶς ἕξουσιν)—apostolic healing ministry confirmed the gospel (Acts 3:1-10, 5:12-16, 28:8). Hand-laying symbolizes impartation of blessing, not magical ritual. James 5:14-15 continues this practice with elders praying over the sick. Healing serves God's redemptive purposes, not human demands—Paul himself left Trophimus sick (2 Timothy 4:20).

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Historical & Cultural Context

Snake-handling cults wrongly use this verse to justify deliberate risk-taking. The verse promises protection in kingdom service, not immunity when tempting God (Matthew 4:7). Early Christians faced poisoning attempts by opponents. The Didache and early church fathers record prayers for healing. Medieval confusion mixed biblical healing with superstition; Reformation recovered biblical practices.

Reflection Questions

  1. How do you distinguish between faith-filled obedience in danger versus presumptuous testing of God?
  2. What does biblical healing ministry look like—should churches today expect the same apostolic signs?
  3. How do you reconcile promised healing with unanswered prayers and persistent illness among believers?

Original Language Analysis

Greek · 17 words
ὄφεις1 of 17

serpents

G3789

a snake, figuratively, (as a type of sly cunning) an artful malicious person, especially satan

ἀροῦσιν2 of 17

They shall take up

G142

to lift up; by implication, to take up or away; figuratively, to raise (the voice), keep in suspense (the mind), specially, to sail away (i.e., weigh

κἂν3 of 17

and if

G2579

and (or even) if

θανάσιμόν4 of 17

deadly

G2286

fatal, i.e., poisonous

τι5 of 17

any

G5100

some or any person or object

πίωσιν6 of 17

they drink

G4095

to imbibe (literally or figuratively)

οὐ7 of 17
G3756

the absolute negative (compare g3361) adverb; no or not

μὴ8 of 17
G3361

(adverb) not, (conjunction) lest; also (as an interrogative implying a negative answer (whereas g3756 expects an affirmative one)) whether

αὐτοὺς9 of 17

them

G846

the reflexive pronoun self, used (alone or in the comparative g1438) of the third person, and (with the proper personal pronoun) of the other persons

βλάψει,10 of 17

hurt

G984

properly, to hinder, i.e., (by implication) to injure

ἐπὶ11 of 17

on

G1909

properly, meaning superimposition (of time, place, order, etc.), as a relation of distribution (with the genitive case), i.e., over, upon, etc.; of re

ἀῤῥώστους12 of 17

the sick

G732

infirm

χεῖρας13 of 17

hands

G5495

the hand (literally or figuratively (power); especially (by hebraism) a means or instrument)

ἐπιθήσουσιν14 of 17

they shall lay

G2007

to impose (in a friendly or hostile sense)

καὶ15 of 17

and

G2532

and, also, even, so then, too, etc.; often used in connection (or composition) with other particles or small words

καλῶς16 of 17

recover

G2573

well (usually morally)

ἕξουσιν.17 of 17

they shall

G2192

to hold (used in very various applications, literally or figuratively, direct or remote; such as possession; ability, contiuity, relation, or conditio


Study Guide

Historical Context

This verse is found in the book of Mark. Understanding the historical and cultural background helps illuminate its meaning for the original audience and for us today.

Theological Significance

Mark 16:18 contributes to our understanding of God's character and His relationship with humanity. Consider how this verse connects to the broader themes of Scripture.

Cross-References

Verses related to Mark 16:18 from Treasury of Scripture Knowledge

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